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Analytical Chem JoVE (Open Access) Citable · DOI

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Name: Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
Uploaded: 2026-10-23
Duration: 10 min 1 s
Description: Learn chemical cross-linking with native mass spectrometry to study multi-subunit protein assembly architecture. This complementary approach reveals composition, connectivity and stoichiometry in structural biology research.

DOI: 10.3791/56747-v

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