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Analytical Chem JoVE (Open Access) Citable · DOI

Detection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR

Name: Detection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR
Uploaded: 2026-10-13
Duration: 10 min 54 s
Description: Learn a PCR-based assay to detect LINE-1 retrotransposition activity in cancer genomes using MCF7 cells. This cost-effective method maps de novo insertions and identifies genomic instability biomarkers.

DOI: 10.3791/59880-v

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