Home › Cell Biology › Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
Cell Biology JoVE (Open Access) Citable · DOI

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

DOI: 10.3791/53420-v
What you'll learn
  • ✓ Set up and conduct event-related potential (ERP) recordings during target-response tasks
  • ✓ Identify ERP differences between affected and unaffected limbs in cerebral palsy
  • ✓ Interpret cognitive processes underlying upper limb disregard in children with unilateral cerebral palsy
Protocol

Several children with unilateral Cerebral Palsy seem to disregard the preserved capacity of their affected upper limb. This Developmental Disregard is extensively described in the literature but the involved cognitive processes have not been studied. To study underlying cognitive factors of upper limb control, an event-related potential protocol was developed.

Difficulty
advanced
Total time
~1.5–2 hours per participant (including EEG setup, task execution, and data acquisition)
Model organism
Human (children with unilateral cerebral palsy)

Steps

1
Introduce visual target-response task protocol

Present the behavioral paradigm where participants respond to visual stimuli using upper limbs. This establishes the task structure for concurrent EEG recording.

▶ 01:06
2
Prepare and apply EEG electrode montage

Apply electrodes according to standard 10–20 placement system for event-related potential recording. Ensure impedance and signal quality before task initiation.

▶ 02:25
3
Execute target-response task during EEG recording

Administer the visual stimulus task while continuously recording EEG data. Monitor signal quality and participant compliance throughout task blocks.

▶ 05:11
4
Analyze event-related potential differences between limbs

Process and compare ERP waveforms (latency, amplitude) evoked by target stimuli for affected versus unaffected upper limb responses. Identify cognitive processing differences.

▶ 06:19
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