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Cell Biology JoVE (Open Access) Citable · DOI

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

DOI: 10.3791/60300-v
What you'll learn
  • ✓ Identify key HRCT imaging patterns diagnostic of systemic sclerosis-associated ILD
  • ✓ Apply practical recommendations for thoracic HRCT scanning protocols in SSc patients
  • ✓ Interpret representative imaging findings to assess disease severity and progression
Protocol

Biopharma Insights Here, we present practical recommendations for performing thoracic high-resolution computed tomography for diagnosing and assessing systemic sclerosis-related interstitial lung disease.

Difficulty
intermediate
Total time
~15–30 min per patient (HRCT acquisition and preliminary interpretation)

Steps

1
Understand systemic sclerosis-associated ILD pathophysiology

Learn the clinical context, disease mechanisms, and imaging rationale for diagnosing SSc-related interstitial lung disease using high-resolution computed tomography.

▶ 00:05
2
Perform high-resolution computed tomography scanning

Apply practical recommendations for acquiring thoracic HRCT images in systemic sclerosis patients, including acquisition parameters and patient positioning.

▶ 00:44
3
Interpret HRCT imaging patterns of SSc-ILD

Recognize and evaluate representative HRCT findings characteristic of systemic sclerosis-associated interstitial lung disease, including fibrotic and non-fibrotic patterns.

▶ 02:07
4
Synthesize imaging assessment for clinical decision-making

Integrate HRCT findings into clinical evaluation and management planning for patients with suspected or confirmed systemic sclerosis-associated ILD.

▶ 03:55
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