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Cell Biology JoVE (Open Access) Citable · DOI

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

DOI: 10.3791/50022-v
What you'll learn
  • ✓ Design and fabricate 2D precursor masks for particle patterning
  • ✓ Prepare substrates and execute origami-inspired self-assembly protocols
  • ✓ Create reconfigurable particles across micro to centimeter scales
Protocol

We describe experimental details of the synthesis of patterned and reconfigurable particles from two dimensional (2D) precursors. This methodology can be used to create particles in a variety of shapes including polyhedra and grasping devices at length scales ranging from the micro to centimeter scale.

Difficulty
advanced
Total time
~4–8 hours per batch (mask design 1–2 hrs, substrate prep 1–2 hrs, assembly 2–4 hrs)

Steps

1
Design masks for patterned particle synthesis

Design 2D mask patterns that will serve as templates for self-assembly. This step defines the final 3D particle geometry and functional features.

▶ 01:56
2
Prepare substrates for particle assembly

Prepare the substrate surface with appropriate coating or modification to enable controlled self-assembly of 2D precursors into 3D structures.

▶ 03:28
3
Execute origami-inspired self-assembly process

Initiate folding and reconfiguration of patterned 2D precursors into target 3D geometries including polyhedra and grasping devices across variable length scales.

▶ 08:25
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