Home › Organic Chemistry › Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core
Organic Chemistry JoVE (Open Access) Citable · DOI

Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core

DOI: 10.3791/56501-v
What you'll learn
  • ✓ Synthesize dibenzothiophene-S,S-dioxide-based TADF emitters at scale
  • ✓ Characterize thermally activated delayed fluorescence compounds
  • ✓ Apply organic coupling reactions for fluorescent material preparation
Protocol

Biopharma Insights Scale-up synthesis of highly efficient thermally activated delayed fluorescence emitters is described in the presented article.

Difficulty
advanced
Total time
~2–3 days per compound (including purification and characterization)

Steps

1
Synthesize 2,8-bis(carbazol-9-yl)dibenzothiophene-S,S-dioxide

Perform coupling reactions to attach carbazole moieties to the dibenzothiophene-S,S-dioxide core. Purify and isolate Compound 4 for subsequent analysis.

▶ 00:45
2
Synthesize 2,8-bis(phenothiazin-10-yl)dibenzothiophene-S,S-dioxide

Perform coupling reactions to attach phenothiazine moieties to the dibenzothiophene-S,S-dioxide core. Purify and isolate Compound 5 for characterization.

▶ 04:39
3
Characterize TADF emitters and fluorescence properties

Analyze synthesized compounds using spectroscopic and photophysical techniques to confirm thermally activated delayed fluorescence behavior and emitter efficiency.

▶ 06:44
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