Home Analytical Chem Use of Electromagnetic Navigational Transthoracic Needle Aspiration (E-TTNA) for Sampling of Lung Nodules
Analytical Chem JoVE (Open Access) Citable · DOI

Use of Electromagnetic Navigational Transthoracic Needle Aspiration (E-TTNA) for Sampling of Lung Nodules

DOI: 10.3791/52723-v
What you'll learn
  • Understand electromagnetic navigation principles for transthoracic needle aspiration
  • Perform tissue sampling of lung nodules using E-TTNA guidance
  • Compare E-TTNA and EBUS-TBNA sampling techniques for diagnostic accuracy
Protocol

We describe the novel use of electromagnetic navigational guided transthoracic needle aspiration for the pathologic assessment of human lung nodules.

Difficulty
advanced
Total time
~30–45 min per patient procedure
Biosafety
BSL-1

Steps

1
Set up electromagnetic navigational aspiration system

Prepare and configure the electromagnetic navigation platform for transthoracic needle guidance. Calibrate imaging and navigation coordinates to ensure accurate real-time tracking of needle position relative to lung nodule anatomy.

▶ 01:12
2
Perform guided tissue sampling procedure

Under electromagnetic navigation, advance the transthoracic needle toward the target lung nodule and obtain tissue samples for pathologic assessment. Monitor needle trajectory and positioning throughout aspiration.

▶ 04:37
3
Compare sampling outcomes with alternative technique

Evaluate tissue yield and diagnostic quality from E-TTNA relative to EBUS-TBNA results to assess relative diagnostic utility of each navigational approach.

▶ 04:59
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