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Biochemistry JoVE (Open Access) Citable · DOI

Visualizing Proteins and Macromolecular Complexes by Negative Stain EM: from Grid Preparation to Image Acquisition

Name: Visualizing Proteins and Macromolecular Complexes by Negative Stain EM: from Grid Preparation to Image Acquisition
Uploaded: 2026-10-13
Duration: 8 min 1 s
Description: Learn negative stain electron microscopy for visualizing purified proteins and macromolecular complexes. This protocol covers grid preparation, staining, and image acquisition for routine structural analysis.

DOI: 10.3791/3227-v

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