Inductively Coupled Plasma Mass Spectrometry ICP-MS Method for Metabolomic Studies Biological Sample

Jason Xu explains that ICP-MS (Inductively Coupled Plasma Mass Spectrometry) can detect metals at part-per-trillion levels and discusses how environmental metals from water, soil, and food impact human health. He emphasizes that ICP-MS is the most advanced and sensitive equipment available, capable of measuring over 30 metals simultaneously in small tissue samples in less than 4 minutes.

The presenter outlines that ICP-MS has a very simple sample treatment method with fast sample preparation, making it an efficient technique for metal analysis.

Xu describes the diverse origins of samples analyzed, including those from the Center for Integrative Environmental Health Sciences (CIEHS) and University of Louisville Health Science campus, as well as collaborations from across Kentucky, the United States, and internationally.

The presenter enumerates the various biological and environmental sample types processed, including water, soil, patient hair, nails, blood, plasma, urine, different tissues, and animal research samples from tissues and fluids.

Xu concludes by announcing that he will now demonstrate how the team analyzes metal concentrations in the prepared samples using the ICP-MS instrument.